All apps
CRISPR-Cas9 — the gene scissors (3D)
About this app
Cas9 with its guide RNA slides along a DNA double helix, checks every PAM site (NGG), unwinds the DNA and forms the R-loop. Only with full pairing do HNH and RuvC cut both strands 3 bp before the PAM. Then choose the repair: end joining (NHEJ) with an insertion or deletion, or precise copying from a template (HDR). A mismatch in the seed prevents the cut. Exhibit-ready.
Subject: Biology & neuroscience
More from Biology & neuroscience
- Aquaporin — water in single file (3D)
- ATP synthase — the cell's motor (3D)
- Eye — eye muscles and vision (3D)
- Fibonacci cactus — one angle, many spirals (3D)
- Gait — walking from real measurements (3D)
- Haemoglobin — cooperativity (3D)
- Explore the heart (3D)
- Cochlea — travelling wave and tonotopy (3D)
A VisuApp by heyprof: interactive, free in your browser, no sign-up. What is a VisuApp? · All apps